Researchers: Gene therapy may treat depression - USATODAY.
Most modern depression drugs aim to affect brain levels of the hormone, serotonin, which was recently linked to p11 in its effects on mood. So, Kaplitt and colleagues, who included Nobel Prize-winning brain cell researcher Paul Greengard of Rockefeller University, first sought to cure mice bred to have depressive symptoms such as listlessness by infecting the "reward center" of their brain with a virus carrying a gene for the protein. The team has pioneered safety experiments aimed at treating human Parkinson's patients with gene therapy.
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